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Ampicillin

Generic Ampicillin
Ampicillin is an antibiotic preparation from the class of medications known as penicillins. This preparation is indicated for the therapy of a variety of infections resulting from microorganisms susceptible to ampicillin (such as bronchitis, acute and chronic urinary tract infections, endocarditis, sepsis, salmonellosis, cholecystitis, etc.)
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What is Ampicillin?
Ampicillin is an antibiotic drug used to treat a number of bacterial infections. This is a drug that has been around a while, earning it a solid reputation. Ampicillin was developed in the 1950’s by the Beecham Company and was approved for use in 1961. Since then, it has skyrocketed to fame and prominence, becoming one of the most widely-used antibiotics all over the globe, with a very reasonable price tag. In fact, this drug is listed on the World Health Organization’s List of Essential Medicines, proving that it is a valuable asset to world health. Ampicillin is effective against both gram-positive and gram-negative bacteria and works by inhibiting the transpeptidase enzyme, which is used by bacteria to create a cell wall. In this way, it stops bacteria from growing and multiplying.

What are the indications for using Ampicillin?
Ampicillin is applied to treat the following conditions:
  • Meningitis – an inflammation of membranes around the brain which is often life-threatening.
  • Endocarditis – a condition characterized by inflammation of inner-heart tissues and the appearance of lesions in the affected area.
  • Salmonella – an infection often picked up by eating raw foods, which is generally not threatening, but which causes diarrhea, vomiting, and fever for up to a week.
  • Otitis media – an inflammation of the inner ear, which affects approximately one-tenth of the world’s population, and kids are affected particularly often.
And a range of other conditions, including respiratory tract infection, urinary tract infection, gonorrhea, pneumonia, bronchitis, and several others.

What is the dosage of Ampicillin?
Ampicillin is usually supplied in the form of 250mg and 500mg capsules. The standard dose of Ampicillin is 500 mg a day, but this can vary based on age, body weight, the type of infection being treated and its severity. As a rule, children will take smaller doses. Though it is typically taken orally, it should be mentioned that the drug can also be injected into the muscle or vein.

What are the contraindications for using Ampicillin?
Ampicillin is not suitable for anyone allergic to the drug, as well as patients who suffer from mononucleosis or infections of penicillinase-creating organisms. It should also be avoided by patients taking penicillin and tetracycline antibiotics, and the oral typhoid vaccine.

What are the adverse effects of Ampicillin?
Clinical trials have proven that a range of side effects from Ampicillin use are possible, including nausea, diarrhea, and rash. In some rare cases, the effects are more severe, and may include anaphylaxis, angioedema, and diarrhea. If you experience one of these severe symptoms, don’t hesitate to contact a doctor.