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Generic Bactrim
Bactrim is an antibiotic medication with two very potent antibiotic substances Trimethoprim and Sulfamethoxazole as its active components. The list of Bactrim indications includes acute otitis media, exacerbation of bronchitis, shigellosis, traveler’s diarrhea, urogenital tract infections such as cystitis, gonorrhea, prostatitis, etc.
  • Expire Date: Feb 2025
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Generic Bactrim 480mg

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What is Bactrim?
Bactrim consists of Trimethoprim and Sulfamethoxazole. Trimethoprim, just like Sulfamethoxazole is an antibiotic used for treating various types of bacterial infection. Bactrim is meant to be used for treating urinary tract infections, ear infections, bronchitis, shigellosis, traveler’s diarrhea, and Pneumocystis jiroveci.

Bactrim can be applied to treat diseases not mentioned in this instruction.

What are the indications for Bactrim?
To prevent further development of a disease caused by drug-resistant bacteria and maintain the efficiency of Bactrim (trimethoprim and sulfamethoxazole) tablets and other antibacterial medicines must be used for treatment of bacterial infections that are strongly suspected or proven to have susceptible bacteria as the cause. When susceptibility information and culture are defined, it’s time to select or modify an antibacterial therapy. If such information is not available, susceptibility patterns and local epidemiology can be useful for selecting of therapy.

What is the dosage for Bactrim?
Adult Dose:

2 regular tablets or 1 DS tablet every 12 hours during 5 days (traveler’s diarrhea, shigellosis) or during 10-14 days (bronchitis). PJP treatment: 15-20 mg/kg every day trimethoprim (75-100 mg/kg every day sulfamethoxazole) in equal dosage every 6 hours during 14-21 days. PJP prophylaxis: 1 DS tablet per day. Renal impairment (CrCl 15-30 mL/min): reduce the dosage by ? CrCl <15mL/min: not advised. Children's Dose: Children of two months: 8mg/kg every day trimethoprim (40mg/kg every day of sulfamethoxazole) in two divided amounts with 12 hour intervals during 5 days (shigellosis) or 10 days (UTIs, otitis media).

What Are the Contraindications for Bactrim?
History of using trimethoprim and or sulfonamides causing drug-induced immune thrombocytopenia. Folate deficiency causing megaloblastic anemia. Risk of hepatic damage. Renal insufficiency if renal status is impossible to monitor.

What Are the Adverse Effects of Bactrim?
Allergic skin reactions, GI upset, blood dyscrasias (megaloblastic anemia), renal or hepatic toxicity, hemolysis, pancreatitis, crystalluria, rash (can be serious: toxic epidermal necrolysis, Stevens-Johnson syndrome), drug fever, lupus-like syndrome, depression, peripheral neuritis, convulsions, hypoglycemia, ataxia, C. difficile associated diarrhea, hyponatremia, hyperkalemia.