Benicar

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Benicar (Olmesartan) is an ARB drug used to control high blood pressure and prevent long-term hypertension associated diseases, primarily strokes, myocardial infarctions, heart and kidney failure. It comes in tablets for oral use, which should be taken once daily. The drug can be administered alone or concomitantly with other antihypertensives.
  • Expire Date: Jun 2021
  • Delivery Time: ~7 days

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What is Benicar?
Benicar is a biologically inactive compound which is metabolized in the body to produce Olmesartan. It is an angiotensin II receptor blocker which works by relaxing blood vessels, improving blood flow and consequently lowering blood pressure. This prodrug comes in solid dosage form with Olmesatran medoxomil as active ingredient. It is intended for oral administration and is typically taken once a day. The drug may take several weeks to take full effect on the blood pressure therefore it is intended for chronic administration.

When is Benicar indicated?
Benicar is indicated for hypertension treatment and cardiovascular events risk reduction (specifically myocardial infarctions and strokes). This prodrug can also be used to treat heart failure and prevent kidney failure. It is approved for use in adult and pediatric patients as young as 6 years old to control blood pressure and minimize the risks associated with long-term hypertension. It can be prescribed alone or together with diuretics or other antihypertensive agents.

How to take Benicar?
Benicar dosage depends on the patient’s medical history and must be individualized. The typical starting dose is 20 mg once daily, which can be raised to 40 mg after 2 weeks of therapy, if necessary. Children are typically administered 10 mg once daily with the dose escalation up to 20 mg after 2 weeks of treatment, if needed. Higher doses or twice-daily dosing schedule do not appear to be more effective. Tablets can be taken without regard to meals, at any but the same time each day.

What are Benicar side effects?
Benicar side effects are typically minor and transient. Patients may experience dizziness at the beginning of treatment as the body adjusts to the medication. Serious side effects are rare but may include unexplained skin rash, difficulty breathing and swallowing, irregular heartbeat, muscle weakness, decreased amount of urine, persistent diarrhea, gastroenteritis, vertigo and hair loss.

When is Benicar contraindicated?
Benicar is contraindicated in coadministration with Aliskiren in diabetic patients. It refers to pregnancy category D, meaning it presents clear risk to the fetus. This prodrug is known to cause face and head deformities when used during pregnancy. It also shouldn’t be prescribed to people with known allergy to Olmesartan medoxomil.