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Cephalexin

Generic Cephalexin
Cephalexin is an antibiotic preparation that has a broad spectrum of action and is active against a large number of various microorganisms. This medication is indicated for the therapy of infectious diseases of different body organs and parts including cystitis, prostatitis, pyelonephritis, bronchitis, otitis, quinsy, sinusitis, furunculosis, etc.
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What is Cephalexin?
Cephalexin is a semisynthetic antibiotic of cephalosporin group intended for oral use. It is effective against a number of bacteria, such as Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, Klebsiella pneumoniae, E. coli and several others that incite strep throat, pneumonia, infections of ear, skin, bones, joints and urinary tract. The antibiotic is available as capsules in a variety of strengths with Cephalexin monohydrate as active ingredient. Being a first generation cephalosporin approved in 1971, it remains in the top 100 most prescribed drugs in the USA.

When is Cephalexin prescribed?
Cephalexin is prescribed for the treatment of otitis media, tonsillitis, sinusitis, streptococcal pharyngitis, bronchitis, pneumonia, osteomyelitis, prostatitis, cellulitis, folliculitis and impetigo. It is also prescribed for prevention of bacterial endocarditis and recurrent urinary infections. The antibiotic is also intended for use in children.

How to take Cephalexin?
Cephalexin dosage ranges from 125 mg to 1000 mg received in several intakes for 7-14 days. The dosing interval is q6h or q12h depending on the kind of infection. For bacterial endocarditis prevention a single dose of 2000 mg is administered one hour before surgery. Pediatric dose is typically 25-100 mg per kg a day in several divided doses. The highest pediatric dose is 4000 mg a day. Capsules must be taken at the same time each day and washed down with plenty of water. If the drug upsets your stomach, capsules should be taken with food.

What are Cephalexin side effects?
Cephalexin may cause hypersensitivity reactions as skin rash, angioedema, fever, urticaria or anaphylaxis and gastrointestinal disturbances as diarrhea, nausea or vomiting. Like other antibiotics it may provoke a pseudomembranous colitis and yeast infection. Hyposensitivity reactions usually subside after discontinuation of the drug. Other side effects are easily treated by attending physician.

When is Cephalexin contraindicated?
Cephalexin is contraindicated to patients with known hypersensitivity to Cephalexin monohydrate or any other cephalosporin antibiotic. Patients with severe kidney disease may require lower doses of the drug. Inform your physician if you are pregnant or breastfeeding. The drug may interact with Probenecid, Aminoglycosides, Metformin and typhoid vaccine.