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Cleocin is prescribed for the treatment of bacterial infections provoked by anaerobic microorganisms that are sensitive to its active component – Clindamycin. Cleocin works by preventing the growth of bacteria; it is indicated for therapy of serious respiratory tract and skin infections as well as infections of the abdomen, female genital tract and pelvis.
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What is Cleocin?
Cleocin, or Clindamycin, as it is also known, is a semi-synthetic lincosamide antibiotic that contains Clindamycin hydrochloride, a hydrated hydrochloride salt of clindamycin. It is made by a 7S chloro-substitution of 7R-hydroxyl group of lincomycin, a parent compound. This antibiotic is able to kill bacteria by stopping the production of the vital proteins the bacteria needs to survive. It is most effective in the treatment of variety of infections caused by anaerobic bacteria. It can also be used as a treatment for protozoal diseases and acne. It has no effect on viral infections.

What are the indications for using Cleocin?
Cleocin is prescribed to patients who are suffering from serious bacterial infections due to susceptible strains of pneumococci, streptococci, and staphylococci. Medical practitioners most often prescribe this drug to individuals who are allergic to penicillin, or for whom penicillin is not a suitable option. Cleocin can also be taken by patients with some protozoal diseases, such as malaria, and by those with methicillin-resistant Staphylococcus aureus infections. This antibiotic can also be administered prior to a dental procedure to individuals with some heart problems. It can prevent serious heart infections. Cleocin is also used in treating acne.

What is the dosage of Cleocin?
The exact dosage of Cleocin depends on the severity of the bacterial infection and response to treatment. Patients with a serious bacterial infection need to take 150 to 300mg of Cleocin four times a day (approximately every 6 hours). Some of the more severe bacterial infections require the drug to be taken in 300-450mg doses, also four times a day. The dosage for children is based on their weight and the severity of the infection. Pediatric patients with a serious infection need to take 8-16mg per kilo per day split into three or four equal doses. The dosage for children with more severe infections is 16-20mg per kilo per day, also to be split into three or four equal doses. Cleocin is a drug that needs to be taken orally with a full glass of water and with or without food. The patient should not lie down in the 10 minutes after taking the drug.

What are the contraindications for using Cleocin?
Cleocin should not be used by patients who are allergic to it, to Lincomycin, or to any of the ingredients in Cleocin. This drug is also not appropriate for patients with certain intestinal problems, such as Crohn disease, antibiotic-associated colitis, ulcerative colitis, Clostridium difficile-associated diarrhea, and others. It is also contraindicated in patients suffering from meningitis. Also, before using this medication, tell your doctor if you have a kidney or liver disease as Cleocin may not be the appropriate medication for you. Cleocin passes into breast milk. Although there have been no reports of harm done to the infants, breastfeeding mothers are generally advised against taking this drug.

What are the adverse effects of Cleocin?
Cleocin can be the cause of a severe, and sometimes fatal, intestinal condition known as Clostridium difficile-associated diarrhea. This condition can appear in the weeks following the conclusion of the treatment. If you notice abdominal and stomach pain, constant diarrhea, or blood and mucus in the stool, get medical help immediately. Some of the more common side effects include vomiting, nausea, and diarrhea. A more serious but unlikely side effect is heartburn. It is crucial that you contact your doctor ASAP if you notice side effects such as dark urine, joint pain or swelling, or the yellowing of the skin or eyes.