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Doxycycline is a semisynthetic antibiotic from the class of drugs called tetracyclines with a broad spectrum of action. It’s is effective against a great variety of bacterial infections including those caused by streptococcus, dysentery bacillus and staphylococcus, typhoid fever, gonorrhea, syphilis, chlamydia, ureaplasmosis and many others.
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What is Doxycycline?
Doxycycline is a broad-spectrum antibiotic of the tetracycline group. It works by reducing bacteria’s ability to produce protein, thus stops their growth and multiplication, allowing the immune system to combat the infection. The antibiotic exerts antibacterial, antiprotozoal and antihelminthic effect. It is available in solid oral dosage form with various strengths.

When is Doxycycline prescribed?
Doxycycline is generally used to cure intestine and urinary infections incited by susceptible microorganisms, including Chlamydia, Mycoplasma, Ureaplasma, Shigella, Streptococcus, Staphylococcus and others. It is prescribed for acne, rosacea, sinusitis, periodontitis, Lyme disease, pelvic inflammatory disease, chronic prostatitis and anthrax. It is also prescribed for prophylactic treatment of malaria. It can be prescribed as penicillin substitute in people with allergy to the latter.

How to take Doxycycline?
Doxycycline is typically administered in a dose of 100 mg q12h on the first day of therapy, followed by 50 mg q12h or 100 mg q24h. The length of therapy is conditioned by the specific infection and its severity, and usually continues for 7-14 days. Children over 8 years of age are initially given 4,4mg/kg in two divided doses, followed by 2,2 mg/kg q12h. Simultaneous food intake doesn’t affect the absorption of the medicine. Plentiful amount of liquid is recommended to avoid ulceration and esophageal irritation.

What are Doxycycline side effects?
Doxycycline is generally well tolerated, though it may spur some side effects predominantly of the gastrointestinal character, including diarrhea, nausea, enterocolitis, dysphagia and glossitis. Rarely it can provoke liver damage, vision changes, intracranial hypertension, hemolytic anemia and thrombocytopenia.

When is Doxycycline contraindicated?
Doxycycline is contraindicated to people who have manifested hypersensitivity to any antibiotics of the tetracycline group. Administration of the antibiotic to children under 8 and to pregnant women in the last trimester of pregnancy may provoke permanent teeth discoloration or enamel hypoplasia. Dairy products, antacids, magnesium containing laxatives, food supplements containing calcium and iron may decrease the efficacy of the antibiotic.