Effexor

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Effexor (Venlafaxine hydrochloride) is a second-generation antidepressant of the SNRI class. It is licensed to treat depression and mood disorders in adults. It is available in tablets with various strengths since its reuptake effects are dose-dependent. Tablets are prescribed orally, 2 or 3 times a day with meals, in a dose depending on the disease severity.
  • Expire Date: Apr 2021
  • Delivery Time: ~7 days

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What is Effexor?
Effexor is an antidepressant and anxiolytic drug of the serotonin-norepinephrine reuptake inhibitors class. It comes in tablets for oral administration and is available in numerous strengths of its main ingredient Venlafaxine hydrochloride. The agent is known to work on the central nervous system by restoring the balance of norepinephrine and serotonin, thus helping to elevate mood and energy level in depressed people.

When is Effexor indicated?
Effexor is primarily indicated for the treatment of major depressive disorder in adults. It may also be used for the treatment of anxiety, obsessive-compulsive disorder, migraines, fibromyalgia, diabetic nerve pain and other neuropathic pain. It is also sometimes used to treat hot flashes in women undergoing menopause. The drug is not approved for depression treatment in children.

How to take Effexor?
Effexor is generally administered twice or thrice daily, with food. The usual starting dosage for depression is 75 mg per day. Depending on the drug tolerance and the need for further clinical effect, the dose can be gradually up-titrated to the maximum daily dose of 225 mg per day. Some patients with severe depression may require as much as 375 mg per day. The dose must be titrated in increments of up to 75 mg per day over no less than 4 days. Patients undergoing hemodialysis and those with hepatic impairment need dose individualization and reduction by 50%. The drug requires gradual withdrawal upon discontinuation.

When is Effexor contraindicated?
Effexor is contraindicated for use in children and anyone allergic to Venlafaxine hydrochloride. The drug mustn’t be used concomitantly with MAOIs. It shouldn’t be prescribed during pregnancy as this can pose risk to carrying fetus to term. The drug can also increase blood and eye pressure, therefore patients with hypertension or glaucoma require close monitoring during the treatment.

What are Effexor side effects?
Effexor can provoke headaches, drowsiness, somnolence, nausea and dry mouth, which usually go away over a 6-week period. Rarely the drug may cause seizures, liver disorders, ejaculation disorder, hair and weight loss. Serious side effects that must be immediately reported to the prescribing physician are aggressiveness, suicidal thoughts, vision changes, chest palpitations and allergy.