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Lisinopril is a long acting ACE inhibitor for managing heart disease and related cardiovascular conditions, including hypertension and cardiac failure. It works by blocking angiotensin-converting enzyme, responsible for narrowing of blood vessels, thus relaxing vessels and lowering blood pressure. The drug comes in tablets intended for once per day use.
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What is Lisinopril?
Lisinopril is a drug commonly used in the treatment of several heart-related conditions. Lisinopril was developed by the Merck pharmaceutical company in the 1980’s, and the drug received approval by the Food and Drug Administration in 1987. In the next decade, it was approved for several more uses by the same organization. This is the third ACE inhibitor drug developed, and it functions by relaxing blood vessels, thus allowing blood to flow more freely. Lisinopril is known under several names, including Prinivil, Tensopril, and Zestril.

What are the indications for using Lisinopril?
Lisinopril is useful in treating several conditions. The first that should be mentioned is hypertension (high blood pressure). This extremely common affliction has many negative health effects, putting strain on the heart and causing disease, failure, and stroke in the long term. Another condition Lisinopril is useful in treating is congestive heart failure. CHF occurs when the heart fails to pump enough blood through the body to meet its demands. This condition puts the patient’s life at risk and causes leg swelling, shortness of breath, tiredness, and limited ability in physical exertion. Lisinopril is also effective in treating acute myocardial infarction and diabetic nephropathy.

What is the dosage of Lisinopril?
Lisinopril is usually provided in the form of 5, 10, or 20 mg tablets, which should be swallowed with a drink of water. The starting dose for all aforementioned conditions is 5 mg once a day, but this dose can be increased or decreased by your doctor based on the effectiveness of your treatment and certain individual factors like age and weight.

What are the contraindications for using Lisinopril?
Lisinopril is dangerous to pregnant and nursing mothers, patients allergic to Lisinopril or its components, as well as those who suffer from angioedema, dialysis, high potassium, and LDL apheresis. Furthermore, Lisinopril is known to interact with some drugs, including ACE inhibitors, aliskiren drugs, lithium, diuretics, antidiabetics, COX-2 inhibitors, and several other categories.

What are the adverse effects of Lisinopril?
In some cases, Lisinopril may cause mild or severe side effects. Mild effects include dizziness, headache, cough, diarrhea and fatigue, while more rare and severe effects may include muscle weakness, irregular heartbeat, gout, impotence, and syncope, among others.