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Prozac (Fluoxetine) is an oral SSRI antidepressant prescribed for clinical depression, panic attacks, OCD, bipolar disorder, bulimia nervosa and some other psychological disorders in pediatric and adult patients. It is prescribed once daily, generally in the morning. The beneficial effect of the medicine may become noticeable in four or more weeks.
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What is Prozac?
Prozac is an antidepressant of the SSRIs class for oral administration. It comes in capsules with various strengths of the active ingredient Fluoxetine hydrochloride. It works by increasing the amount of serotonin in the brain, helping to maintain mental balance. The agent may improve mood, energy level, appetite, sleep and heighten the interest in daily living. It may also decrease anxiety, fear, panic attacks and reduce the urge to perform repeated tasks or compulsions.

When is Prozac indicated?
Prozac is widely applied in mental health treatment. It is indicated for the management of depression, panic disorder, obsessive-compulsive disorder, bulimia, PTSD and premenstrual dysphonic disorder. It can be applied in combination therapy for bipolar disorder treatment. The agent is also used for obesity, alcohol dependence, binge eating disorder and cataplexy. It is approved for use in adults and licensed to treat OCD and depression in children and adolescents.

How to take Prozac?
Prozac should be taken by mouth, typically once a day. Pills can be taken without regard to meals. The staring dosage for bulimia is 60 mg. Treatment of OCD and depression usually starts at 20 mg. Panic disorder treatment is initiated at 10 mg with the dose escalation to 20 mg after one week. Geriatric patients may require starting at lower doses. The dosage for children and adolescents is typically 10 mg or 20 mg once a day. It may take 4-5 weeks for the drug to take full effect. Tapering off the dose may be needed to avoid discontinuation syndrome.

What are Prozac side effects?
Prozac may cause insomnia, nausea, headache, loss of appetite, dyspepsia, sweating, rash, drowsiness, tremor, anxiety, decreased libido and erection problems. In rare cases the drug may cause canker sores, acne and elevated cholesterol. More serious side effects include suicidal thoughts and behavior, panic attacks and hallucinations, which are more common among patients younger than 25.

When is Prozac contraindicated?
Prozac is contraindicated to people hypersensitive to Fluoxetine. In order to avoid potential serotonin syndrome, the drug shouldn’t be used concomitantly with Pimozide or Thioridazine. Patients should wait at least 2 weeks before starting the medication after prior treatment with MAOIs or wait for 5 weeks after stopping Prozac before initiating treatment with Phenelzine or Tranylcypromine.