Roaccutane

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Roaccutane an antiseborrheic, anti-inflammatory agent that belongs to the class of retinoids. It acts by decreasing sebum production and correcting abnormal keratinization. It is primarily used for recalcitrant cystic acne treatment and is intended for oral administration. The drug is taken twice daily with food for 6-8 months.
  • Expire Date: Feb 2021
  • Delivery Time: ~7 days

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What is Roaccutane?
Roaccutane is a drug licensed to treat severe cystic acne that is resistant to other antibacterial and topical treatments. It comes in capsules for oral administration, which contain various strengths of the active pharmaceutical ingredient Isotretinoin. It is a retinoid that is chemically related to vitamin A and is naturally found in the human body. The agent works by affecting sebaceous glands and decreasing sebum production. It also normalizes skin keratinization, when skin cells build up within hair follicles adding to the skin problem.

When is Roaccutane indicated?
Roaccutane is indicated for the treatment of severe recalcitrant cases of nodular acne that haven’t responded to other treatments. It is also used to treat grave and sometimes fatal skin diseases as harlequin ichthyosis and lamer ichthyosis, and to prevent certain types of skin cancer. The drug can be prescribed to adults and adolescents aged 12 and over. However, due to high probability of adverse effects it is typically reserved for severe cases of nodular acne, when other acne treatments have failed.

How to take Roaccutane?
Roaccutane is administered twice daily in a dose calculated upon the weight of the patient, severity of acne and individual response to the drug. The usual recommended dose is 0,5-1mg per kg of body weight. The drug should be taken with food. The course of administration lasts from 4 to 8 months. In some patients acne may worsen during the first days of therapy and improvements can be seen in a month or two; however acne will continue to get better after stopping taking the pills. If acne returns, a new course of medication may be required.

What are Roaccutane side effects?
Roaccutane side effects are usually similar to those spurred by high doses of vitamin A: dryness of skin, lips, eyes and nasal passage. The drug can also cause high blood pressure and related to it symptoms: headache, fatigue, nausea, vomiting and vision changes. In rare cases it may cause psychiatric changes as depression, anxiety, changes in sleep pattern, hallucinations, suicidal thoughts.

When is Roaccutane contraindicated?
Roaccutane is referred to pregnancy category X, meaning it is categorically contraindicated to pregnant women or those who may become pregnant as there is a high risk to cause severe birth defects. Women who want to get pregnant must wait at least 1 month after stopping the drug before conceiving.