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> Blood pressure-cardiology > Zocor

Zocor online
Brand Name: Zocor
Manufactured: Merck Sharp & Dohme
Active Ingradients: simvastatin

Therapeutic actions: Simvastatin decreases the production of LDL cholesterol by blocking the action of the enzyme in the liver that is responsible for its production.
 
DRUGS FORM Q-TY PRICE ORDER
Zocor 10mg Tablet 28 42.75 $
 
Zocor 20mg Tablet 28 56.14 $
 
 
GENERIC Zocor
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What is it used for?
• High blood cholesterol levels (primary hypercholesterolaemia).
• Inherited high blood cholesterol levels (familial hypercholesterolaemia).
• High levels of any or all of the fats in the blood, such as cholesterol, triglycerides and lipoproteins (mixed hyperlipidaemia).
• Reducing risk of death and illness from coronary heart disease in people who have had a heart attack, or who have angina or diabetes.

Contraindications and cautions:

Use with caution in
• People over 70 years of age.
• Decreased kidney function.
• Underactive thyroid gland (hypothyroidism).
• Personal or family history of hereditary muscle disorders.
• History of muscular side effects during previous treatment with a statin or fibrate medicine.
• History of liver disease.
• People who drink large quantities of alcohol.
• Hereditary blood disorders called porphyrias.
Not to be used in
• Active liver disease.
• People with unexplained raised results in liver function tests.
• Breastfeeding.
• Pregnancy.
• People taking the antifungals itraconazole or ketoconazole, the antibiotics erythromycin, clarithromycin or telithromycin, a protease inhibitor for HIV infection, or the antidepressant nefazodone.
• Rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption (Zocor tablets contain lactose).
• There is insufficient information regarding the safety and efficacy of this medicine in children. It is not recommended for children.
This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
Certain medicines should not be used during pregnancy or breastfeeding.
It is recommended that you avoid drinking excessive amounts of alcohol while taking this medicine.
You should avoid drinking grapefruit juice while taking this medicine.

Side effects:
Medicines and their possible side effects can affect individual people in different ways. Just because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect. The following are some of the side effects that are known to be associated with this medicine:
• abdominal pain
• constipation
• flatulence
• feeling of weakness
• headache
• dizziness
• pins and needles (paraesthesia)
• indigestion
• nausea and vomiting
• diarrhoea
• anaemia
• liver disorders
• rash or itching
• hair loss
• muscle disorders.
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.

Interactions:
It is important to tell your doctor what medicines you are taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine.
There may be an increased risk of side effects on the muscles (myopathy) if this medicine is taken with any of the following medicines:
• amiodarone
• ciclosporin
• clarithromycin
• danazol
• diltiazem
• erythromycin
• ezetimibe
• fibrates for lowering cholesterol, eg bezafibrate, gemfibrozil
• itraconazole
• ketoconazole
• nefazadone
• nicotinic acid or niacin
• protease inhibitors for HIV infection, eg nelfinavir
• telithromycin
• verapamil
These medicines should be avoided where possible in people taking simvastatin. If treatment with the antifungals itraconazole or ketoconazole, or the antibiotics erythromycin, clarithromycin or telithromycin is unavoidable, therapy with simvastatin must be suspended during the course of treatment.

The anti-blood-clotting effect of anticoagulants such as warfarin may be increased by simvastatin.
The following medicines may reduce the amount of simvastatin in your blood and could make it less effective:
• efavirenz
• rifampicin
• the herbal remedy St John's wort (Hypericum perforatum).
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