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Zyban (Bupropion) is an atypical antidepressant also used for treating nicotine addiction. It acts by blocking reuptake of certain brain chemicals and can be administered together with smoking cessation counseling. Treatment is initiated while still smoking, with the goal of complete abstinence in 7 to 12 weeks. Tablets are administered twice daily.
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What is Zyban?
Zyban is an atypical antidepressant drug with several uses. It is known under several other trade names, including Wellbutrin and Elontril though it is officially named Bupropion. This drug was developed by Nariman Mehta, an Indian researcher working at Burroughs Wellcome, a company now called GlaxoSmithKline. Though Zyban was patented in 1969, it did not receive approval from the Food and Drug Administration until 1985. Initially, the strength of the drug was too high and caused seizures in some patients, but this problem was sorted out, and Zyban became a best-selling drug around the world. Like most psychiatric medications, Zyban functions by restoring the balance of neurotransmitters in the brain.

What are the indications for using Zyban?
The most common use for Zyban is as an aid to quit smoking. Smoking is a nasty habit that harms the body in many ways and causes various cancers. Zyban helps relieve withdrawal symptoms and reduces the urge to smoke. Furthermore, Zyban is often used to treat depression. This is a serious condition millions of people suffer from, which prevents them from leading healthy and happy lives. In this regard, Zyban acts as an antidepressant but doesn’t cause certain common negative side effects associated with drugs of this category.

What is the dosage of Zyban?
Zyban is supplied in the form of 150 mg tablets. Dosage and treatment length vary based on the condition the patient is treating. For smoking cessation, the first three days of treatment should include a daily dose of 150 mg, but this dose should be boosted up to 300 mg after this period. 300 mg should be divided into two doses no less than 8 hours apart. Treatment will usually take several months.

What are the contraindications for using Zyban?
Zyban should be avoided by anyone allergic to the drug or suffering from epilepsy, bulimia, anorexia, or brain tumors. Doctors should be consulted by patients with serious hypertension, liver damage and kidney disease. Zyban should not be taken with alcohol or drugs that interact with it, including monoamine oxidase inhibitors, benzodiazepine, antipsychotics, antidepressants, dopaminergics, and corticosteroids.

What are the adverse effects of Zyban?
Recorded side effects of Zyban include hypertension, seizure, glaucoma, psychosis, insomnia and dry mouth. If you experience any severe side effects from Zyban use, get medical help as soon as possible.